cosmic-database

Quick Review

Excellent skill for accessing COSMIC cancer mutation database with comprehensive documentation. The SKILL.md provides clear descriptions of when to use the skill, detailed authentication requirements, and multiple usage patterns (Python API and CLI). Task knowledge is strong with concrete code examples for downloading various data types (mutations, gene census, signatures, fusions), working with different file formats (TSV, VCF, CSV), and common analysis patterns. Structure is well-organized with clear sections, though it's slightly verbose for SKILL.md (some data type details could be moved to referenced files). Novelty is moderate-to-good: while downloading files via authenticated API isn't extremely complex, the skill provides valuable abstraction over COSMIC's authentication system, shortcuts for common file paths, and domain-specific knowledge about cancer genomics data types that would require significant research and tokens for a CLI agent to replicate. The skill meaningfully reduces friction for biomedical researchers working with cancer mutation data.